Isotopically Labeled Compounds
Medchemexpress LLC Benzyl Paraben-d7 | 1216916-40-3 | 235.29 | 5 MG
Benzyl Paraben-d7 is a deuterium-labeled Benzyl 4-hydroxybenzoate, which is a prominent material used as an excipient. It can function as a bacteriostatic agent or preservative in pharmaceutical preparations, improving stability, solubility, and processability. Excipients also influence the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs. This product is for research use only and has not been fully validated for medical applications.
- Deuterium-labeled compound
- Can be used as a bacteriostatic agent
- Functions as a preservative
- Improves stability and solubility of pharmaceutical preparations
- Affects ADME processes of co-administered drugs
Medchemexpress LLC SN-38-d3 | 718612-49-8 | MFCD09841270 | 98.8% | 395.42 | C22H17D3N2O5 | 5 MG
SN-38-d3 is the deuterium-labeled analogue of SN-38, the active metabolite of irinotecan. Supplied as a high-purity stable isotope standard, it is intended for use as a tracer or internal standard in quantitative analytical methods and preclinical studies involving topoisomerase I activity.
- Deuterium-labeled internal standard for quantitative analysis.
- High purity: 98.8%.
- Suitable for NMR, GC-MS, and LC-MS workflows.
- Useful as a tracer or internal standard in ADC payload and topoisomerase I research.
- Available in small analytical pack sizes for laboratory use.
Medchemexpress LLC Difelikefalin-d5 hydrochloride (CR-845-d5 hydrochloride) | 1024828-77-0 | 97.6% | 794.26 | 1 MG
Difelikefalin-d5 (CR-845-d5) hydrochloride is the deuterium-labeled Difelikefalin. It acts as a peripherally restricted and selective agonist of the kappa opioid receptor (KOR), demonstrating anti-inflammatory effects and potentially modulating pruritus in conditions such as chronic kidney disease.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Glutaric acid-d4 | 19136-99-3 | 99.5% | 136.14 | 25 MG
Glutaric acid-d4 is a deuterium-labeled form of Glutaric acid. Glutaric acid is a C5 dicarboxylic acid that plays a role as an intermediate in the catabolic pathways of lysine and tryptophan. It has been observed to influence pericyte contractility and migration. Additionally, Glutaric acid is recognized as an indicator for glutaric aciduria type I. This product is intended for research use only.
- Used as a tracer in research applications.
- Suitable as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Heavy isotopes like deuterium can impact the pharmacokinetic and metabolic profiles of pharmaceutical compounds.
Cambridge Isotope Laboratories 4-Bromo-2 3 3 4-tetraCB (13C12 99%) 40 ug/mL in nonane 3 mL
4-Bromo-2 3 3 4-tetraCB (13C12 99%) 40 ug/mL in nonane 3 mL
Medchemexpress LLC Docosanoic acid-d43 (Behenic acid-d43) | 29823-26-5 | 99.3% | 383.85 | 10 MG
Docosanoic acid-d43 (Behenic acid-d43) is the deuterium-labeled Docosanoic acid. Docosanoic acid is a long-chain saturated fatty acid. It inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Nonan-1-ol-d19 | 349553-86-2 | 98.0% | 163.37 | 25 MG
Nonan-1-ol-d19 is a deuterium-labeled Nonan-1-ol. Stable heavy isotopes of hydrogen, carbon, and other elements, such as deuterium, have been incorporated into drug molecules for use as tracers in drug development and to study their impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Avanti Polar Lipids C18:0 GM1-D5 (SYNTHETIC)-100UG
C18:0 GM1-d5 (synthetic)C18:0 GM1 Ganglioside-d5 (synthetic, ammonium salt), 100UG
Medchemexpress LLC DL-Proline-d7 | 65807-21-8 | 98.0% | 122.17 | 100 MG
DL-Proline-d7 is the deuterium-labeled form of DL-Proline (HY-W012908). It serves as a biochemical reagent suitable for use as a biological material or organic compound in life science-related research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes into drug molecules aids in quantitation during the drug development process.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Revvity Health Sciences Inc Chromium-51 Radionuclide, 2mCi (74MBq), Sodium Chromate in Normal Saline (pH 8-10)
Chromium-51 Radionuclide, 2mCi (74MBq), Sodium Chromate in Normal Saline (pH 8-10)
Cayman Chemical PlerIxafor-d4 1mg
An internal standard for the quantification of plerixafor by GC- or LC-MS